Evaluation of Intensive Statins and Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors on Intracranial Artery Plaque Stability: A Prospective Single‐Arm Study

Evaluation of Intensive Statins and Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors on Intracranial Artery Plaque Stability: A Prospective Single‐Arm Study

Background Intracranial atherosclerotic stenosis is a leading cause of ischemic stroke and recurrent events due to plaque instability. High‐resolution magnetic resonance imaging identifies plaque enhancement as a key marker of instability. This study evaluated the efficacy of combined high‐intensity...

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Main Authors: Weiqi Zeng, Feng Zhou, Hai Zhao, Yukai Wang, Jingjuan Chen, Jiancong Lu, Dezhi Zheng, Jingyun Kuang, Dahua Yuan, Jing Zhou, Changzheng Shi, Xihai Zhao, Xinyi Leng, Bernard Yan, Zefeng Tan
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
HR‐MRI
intracranial atherosclerotic stenosis
ischemic stroke
PCSK9 inhibitor
plaque stability
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.035651
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https://www.ahajournals.org/doi/10.1161/JAHA.124.035651

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