Single-nucleus transcriptomics reveal the cytological mechanism of conjugated linoleic acids in regulating intramuscular fat deposition

Single-nucleus transcriptomics reveal the cytological mechanism of conjugated linoleic acids in regulating intramuscular fat deposition

Conjugated linoleic acids (CLAs) can serve as a nutritional intervention to regulate quality, function, and fat infiltration in skeletal muscles, but the specific cytological mechanisms remain unknown. Here, we applied single-nucleus RNA-sequencing (snRNA-seq) to characterize the cytological mechani...

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Bibliographic Details
Main Authors: Liyi Wang, Shiqi Liu, Shu Zhang, Yizhen Wang, Yanbing Zhou, Tizhong Shan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-03-01
Series:eLife
Subjects:
single-nucleus RNA-sequencing
conjugated linoleic acid
skeletal muscle
fibro/adipogenic progenitors
fat infiltration
pig
Online Access:https://elifesciences.org/articles/99790
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https://elifesciences.org/articles/99790

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