The effect of vagus nerve stimulation on heart rate and respiration rate and their impact on seizure susceptibility in anaesthetized rats under pentylenetetrazol

Despite the proven efficacy of vagus nerve stimulation (VNS) in seizure control, its precise mechanism of action remains unclear. VNS is known to impact the cardiorespiratory system. In this study, we explored the effects of standard and breathing-synchronized VNS on heart and respiratory rates in a...

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Main Authors: Javier Chávez Cerda, Elena Acedo Reina, Ayse S. Dereli, Louis Vande Perre, Romain Raffoul, Maxime Verstraeten, Michel-Antony Ngan Yamb, Enrique Germany Morrison, Elise Collard, Auriane Apaire, Pascal Doguet, Jérôme Garnier, Jean Delbeke, Riëm El Tahry, Antoine Nonclercq
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1487082/full
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