New Onset Insomnia in a Pediatric Patient: A Case of Anti-NMDA Receptor Encephalitis

Anti-NMDAR encephalitis is becoming more widely recognized as a cause of encephalopathy in both adults and children. Certain clinical features such as mood lability, movement disorders, speech dysfunction, seizures, and autonomic instability in a pediatric patient should prompt immediate concern and...

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Main Authors: Tamar N. Goldberg, Michael F. Cellucci
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2017/4083785
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author Tamar N. Goldberg
Michael F. Cellucci
author_facet Tamar N. Goldberg
Michael F. Cellucci
author_sort Tamar N. Goldberg
collection DOAJ
description Anti-NMDAR encephalitis is becoming more widely recognized as a cause of encephalopathy in both adults and children. Certain clinical features such as mood lability, movement disorders, speech dysfunction, seizures, and autonomic instability in a pediatric patient should prompt immediate concern and evaluation for autoimmune encephalitis among providers. We present the case of a pediatric patient with anti-NMDAR encephalitis in which the symptom prompting medical evaluation was insomnia. Insomnia has not previously been emphasized in the literature as a presenting feature of this disease in children and has a broad differential. Recognition of the symptoms of anti-NMDAR encephalitis and its variable presentation are key to early diagnosis and prompt initiation of treatment which may help to improve outcomes.
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institution Kabale University
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series Case Reports in Pediatrics
spelling doaj-art-d46ffa355a5c43149116119c72cdeb9a2025-02-03T05:46:27ZengWileyCase Reports in Pediatrics2090-68032090-68112017-01-01201710.1155/2017/40837854083785New Onset Insomnia in a Pediatric Patient: A Case of Anti-NMDA Receptor EncephalitisTamar N. Goldberg0Michael F. Cellucci1Department of Pediatrics, Sidney Kimmel Medical College/Alfred I. duPont Hospital for Children Pediatric Residency Program, Wilmington, DE, USADivision of Diagnostic Referral, Department of Pediatrics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USAAnti-NMDAR encephalitis is becoming more widely recognized as a cause of encephalopathy in both adults and children. Certain clinical features such as mood lability, movement disorders, speech dysfunction, seizures, and autonomic instability in a pediatric patient should prompt immediate concern and evaluation for autoimmune encephalitis among providers. We present the case of a pediatric patient with anti-NMDAR encephalitis in which the symptom prompting medical evaluation was insomnia. Insomnia has not previously been emphasized in the literature as a presenting feature of this disease in children and has a broad differential. Recognition of the symptoms of anti-NMDAR encephalitis and its variable presentation are key to early diagnosis and prompt initiation of treatment which may help to improve outcomes.http://dx.doi.org/10.1155/2017/4083785
spellingShingle Tamar N. Goldberg
Michael F. Cellucci
New Onset Insomnia in a Pediatric Patient: A Case of Anti-NMDA Receptor Encephalitis
Case Reports in Pediatrics
title New Onset Insomnia in a Pediatric Patient: A Case of Anti-NMDA Receptor Encephalitis
title_full New Onset Insomnia in a Pediatric Patient: A Case of Anti-NMDA Receptor Encephalitis
title_fullStr New Onset Insomnia in a Pediatric Patient: A Case of Anti-NMDA Receptor Encephalitis
title_full_unstemmed New Onset Insomnia in a Pediatric Patient: A Case of Anti-NMDA Receptor Encephalitis
title_short New Onset Insomnia in a Pediatric Patient: A Case of Anti-NMDA Receptor Encephalitis
title_sort new onset insomnia in a pediatric patient a case of anti nmda receptor encephalitis
url http://dx.doi.org/10.1155/2017/4083785
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AT michaelfcellucci newonsetinsomniainapediatricpatientacaseofantinmdareceptorencephalitis