Injectable Hierarchical Bioactive Hydrogels with Fibroblast Growth Factor 21/Edaravone/Caffeic Acid Asynchronous Delivery for Treating Parkinson's Disease

Injectable Hierarchical Bioactive Hydrogels with Fibroblast Growth Factor 21/Edaravone/Caffeic Acid Asynchronous Delivery for Treating Parkinson's Disease

Abstract Parkinson's disease (PD) is one of the most common long‐term neurodegenerative disorders, with multiple comorbid psychiatric and behavioral abnormalities. The combination of clinical drugs targeting different symptoms with smart hydrogels to achieve asynchronous releases is highly tran...

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Main Authors: Junpeng Xu, Peng Dai, Chen Zhang, Na Dong, Caiyan Li, Chonghui Tang, Zhihao Jin, Shih‐Ho Lin, Luyang Ye, Tianmiao Sun, Yukai Jin, Fenzan Wu, Lihua Luo, Ping Wu, Shengcun Li, Xiaokun Li, Shan‐hui Hsu, Dawei Jiang, Zhouguang Wang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
asynchronous release
bioactive hydrogel
fibroblast growth factor
Parkinson's disease
triple‐drug delivery system
Online Access:https://doi.org/10.1002/advs.202412020
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https://doi.org/10.1002/advs.202412020

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