Suppression of Peroxisomal Enzyme Activities and Cytochrome P450 4A Isozyme Expression by Congeneric Polybrominated and Polychlorinated Biphenyls

The purpose of this study was to determine the effects of PCBs and PBBs on peroxisome proliferator-activated receptor-α-(PPARα-) associated enzyme activities or protein levels. Male Sprague-Dawley rats were administered a single IP injection (150 μmol/kg) of either 3,3′,4,4′-tetrabromobiphenyl, 3,3′...

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Bibliographic Details
Main Authors: Larry W. Robertson, Isabelle Berberian, Tim Borges, Li-Chuan Chen, Ching K. Chow, Howard P. Glauert, Johannes G. Filser, Helmut Thomas
Format: Article
Language:English
Published: Wiley 2007-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2007/15481
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