Cancer liquid biopsies by Oxford Nanopore Technologies sequencing of cell-free DNA: from basic research to clinical applications

Cancer liquid biopsies by Oxford Nanopore Technologies sequencing of cell-free DNA: from basic research to clinical applications

Abstract Liquid biopsies, in particular, analysis of cell-free DNA, are expected to revolutionize the current landscape of cancer diagnostics and treatment. However, the existing methods for cfDNA-based liquid biopsies for cancer have certain limitations, such as fragment interruption and GC bias, w...

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Bibliographic Details
Main Authors: Hua-Qi Si, Peng Wang, Fei Long, Wei Zhong, Yuan-Dong Meng, Yuan Rong, Xiang-Yu Meng, Fu-Bing Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Molecular Cancer
Subjects:
Oxford Nanopore Technologies
Cell-free DNA
Oncology
Liquid biopsies
Diagnosis
Personalized medicine
Online Access:https://doi.org/10.1186/s12943-024-02178-6
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