Piezo1 promotes intervertebral disc degeneration through the Ca2+/F-actin/Yap signaling axis

Abstract Background Piezo1 is a mechanically sensitive cation channel expressed in various tissues of the human body and has multiple roles in both physiological and pathological processes. However, its role in the occurrence and development of intervertebral disc degeneration (IVDD) is not fully un...

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Bibliographic Details
Main Authors: Fushuai Peng, Mingtong Sun, Xingzhi Jing, Fei Chen, Tong Cao, Zhenzhen Li, Tao Li
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-025-01147-z
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