Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel

Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel

Abstract Fc‐gamma receptor (FcγR) activation by soluble IgG immune complexes (sICs) represents a major mechanism of inflammation in certain autoimmune diseases such as systemic lupus erythematosus (SLE). A robust and scalable test system allowing for the detection and quantification of sIC bioactivi...

Full description

Saved in:
Bibliographic Details
Main Authors: Haizhang Chen, Andrea Maul‐Pavicic, Martin Holzer, Magdalena Huber, Ulrich Salzer, Nina Chevalier, Reinhard E Voll, Hartmut Hengel, Philipp Kolb
Format: Article
Language:English
Published: Springer Nature 2021-11-01
Series:EMBO Molecular Medicine
Subjects:
immune complexes
Fc‐gamma receptors
FcγR activation
SLE
Online Access:https://doi.org/10.15252/emmm.202114182
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.15252/emmm.202114182

Similar Items