Dissecting macrophage heterogeneity and kaempferol in lung adenocarcinoma: a single-cell transcriptomic approach and network pharmacology
Abstract Background Lung adenocarcinoma (LUAD) is a leading form of non-small cell lung cancer characterized by a complex tumor microenvironment (TME) that influences disease progression and therapeutic response. Tumor-associated macrophages (TAMs) within the TME promote tumorigenesis and evasion of...
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Main Authors: | Laiyi Wan, Wentao Hao, Leilei Li, Lin Wang, Yanzheng Song |
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Format: | Article |
Language: | English |
Published: |
Springer
2025-01-01
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Series: | Discover Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s12672-025-01832-9 |
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