Computational Study Protocol: Leveraging Synthetic Data to Validate a Benchmark Study for Differential Abundance Tests for 16S Microbiome Sequencing Data [version 2; peer review: 2 approved]
Background Synthetic data’s utility in benchmark studies depends on its ability to closely mimic real-world conditions and reproduce results obtained from experimental data. Building on Nearing et al.’s study (1), who assessed 14 differential abundance tests using 38 experimental 16S rRNA datasets i...
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Main Authors: | Clemens Kreutz, Eva Kohnert |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2025-01-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/13-1180/v2 |
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