Computational Study Protocol: Leveraging Synthetic Data to Validate a Benchmark Study for Differential Abundance Tests for 16S Microbiome Sequencing Data [version 2; peer review: 2 approved]

Background Synthetic data’s utility in benchmark studies depends on its ability to closely mimic real-world conditions and reproduce results obtained from experimental data. Building on Nearing et al.’s study (1), who assessed 14 differential abundance tests using 38 experimental 16S rRNA datasets i...

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Bibliographic Details
Main Authors: Clemens Kreutz, Eva Kohnert
Format: Article
Language:English
Published: F1000 Research Ltd 2025-01-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/13-1180/v2
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