Novel multifunctional targeted nanozyme as an ultrasound contrast agent for real-time monitoring and treatment of congenital hydronephrosis renal fibrosis

Abstract Background Congenital Hydronephrosis (CH) is a common pediatric disorder that often leads to renal fibrosis (RF), significantly impairing kidney function. Oxidative stress (OS) plays a central role in the pathogenesis of RF. Current treatments lack effective monitoring and targeted therapie...

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Bibliographic Details
Main Authors: Qian Zhao, Di Zhang, Keyan Chen, Feifei Sun, Yixin Chen
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-025-03618-1
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