Particulate matter and co-occurring genetic risk induce oxidative stress and cardiac and brain Alzheimer’s pathology

Particulate matter and co-occurring genetic risk induce oxidative stress and cardiac and brain Alzheimer’s pathology

Abstract Amyloid-beta (Aβ) aggregates, an Alzheimer’s disease (AD) pathological hallmark, extend beyond the brain to the heart of heart failure (HF) and AD patients. Being diseases of the elderly, increased prevalence is expected as the population ages. However, changes in the incidence and prevalen...

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Main Authors: Helen M. Butler, Everette Keller, Marice McCrorey, Gizem Keceli, Colin K. Combs, Rakez Kayed, Rajasekaran Namakkal-S, Nazareno Paolocci, Bethany Jacobs Wolf, Loren E. Wold, Federica del Monte
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07701-z
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https://doi.org/10.1038/s42003-025-07701-z

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