GLAD-PCR assay of DNA methylation sites in regulatory regions of some tumor-suppressor genes in breast cancer

GLAD-PCR assay of DNA methylation sites in regulatory regions of some tumor-suppressor genes in breast cancer

Hypermethylation of the RcgY sites is shown for many cancer diseases. such aberrant methylation, suppressing the gene activity, occurs at early stages of carcinogenesis. Recently, using glad-pcR assay, we have detected aberrantly methylated RcgY sites, which can be considered to be epigenetic marker...

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Bibliographic Details
Main Authors: N. A. Smetannikova, M. A. Abdurashitov, A. G. Akishev, P. I. Pozdnyakov, E. V. Dubinin, A. B. Karpov, I. V. Vihlyanov, M. K. Nikitin, S. M. Soldatova, N. A. Netesova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2022-01-01
Series:Сибирский онкологический журнал
Subjects:
breast cancer
tumor-suppressor genes
dna methylation
glad-pcr assay
Online Access:https://www.siboncoj.ru/jour/article/view/1984
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