Role of B7‐H3 in predicting response to neoadjuvant chemotherapy in muscle‐invasive bladder cancer

Role of B7‐H3 in predicting response to neoadjuvant chemotherapy in muscle‐invasive bladder cancer

Abstract Background Neoadjuvant platinum‐based chemotherapy offers a modest survival advantage in muscle‐invasive bladder cancer (MIBC) for patients with pathologic response. B7‐H3 (CD276), an immune checkpoint overexpressed in various cancers, including urothelial‐cell carcinoma (UCC), has been ass...

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Main Authors: Ekamjit S. Deol, Reza Nabavizadeh, Roxane R. Lavoie, Mihai G. Dumbrava, Edlira Horjeti, Prabin Thapa, John C. Cheville, Igor Frank, Fabrice Lucien
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:BJUI Compass
Subjects:
biomarkers
bladder cancer
cystectomy
neoadjuvant chemotherapy
Online Access:https://doi.org/10.1002/bco2.418
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https://doi.org/10.1002/bco2.418

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