Bioenergetic consequences of PINK1 mutations in Parkinson disease.

Bioenergetic consequences of PINK1 mutations in Parkinson disease.

<h4>Background</h4>Mutations of the gene for PTEN-induced kinase 1 (PINK1) are a cause of familial Parkinson's disease (PD). PINK1 protein has been localised to mitochondria and PINK1 gene knockout models exhibit abnormal mitochondrial function. The purpose of this study was to dete...

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Bibliographic Details
Main Authors: Andrey Yurevich Abramov, Matthew Gegg, Anne Grunewald, Nicholas William Wood, Christine Klein, Anthony Henry Vernon Schapira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0025622&type=printable
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