LDHA-induced histone lactylation mediates the development of osteoarthritis through regulating the transcription activity of TPI1 gene

Osteoarthritis (OA) is a worldwide joint disease, leading to the physical pain, stiffness, and even disability. Lactate dehydrogenase A (LDHA) is known as a lactylation mediator that can regulate histone lactylation of its target genes. However, the role of LDHA-mediated histone H3 lysine 18 lactyla...

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Bibliographic Details
Main Authors: Junfeng Xia, Zongrui Qiao, Xiao Hao, Yin Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autoimmunity
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Online Access:https://www.tandfonline.com/doi/10.1080/08916934.2024.2384889
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