Autophagy and extracellular vesicles mediate cisplatin resistance in oral squamous cell carcinoma with LC3B-II as a potential non-invasive biomarker

Autophagy and extracellular vesicles mediate cisplatin resistance in oral squamous cell carcinoma with LC3B-II as a potential non-invasive biomarker

Abstract Drug resistance remains a critical challenge in cancer chemotherapy, particularly in oral squamous cell carcinoma (OSCC). Recent findings have highlighted the significant roles that autophagy and extracellular vesicles (EVs) play in contributing to chemoresistance. In previous studies, we d...

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Bibliographic Details
Main Authors: Kar-Yan Su, Xin-Hui Khoo, Ian C. Paterson, Bey-Hing Goh, Wai-Leng Lee
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Oral cancer
Biomarkers
Extracellular vesicles
Autophagy
Drug resistance
Bioinformatics
Online Access:https://doi.org/10.1038/s41598-025-00703-1
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https://doi.org/10.1038/s41598-025-00703-1

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