Comparison of 5 BMPs for their chondrogenic potentials and microfracture-mediated cartilage repair using heparin/PEAD coacervate sustained release polymer

Comparison of 5 BMPs for their chondrogenic potentials and microfracture-mediated cartilage repair using heparin/PEAD coacervate sustained release polymer

Cartilage defect repair and osteoarthritis treatments remain clinical challenges. Microfracture is a commonly used surgical procedure for the treatment of cartilage defects but often leads to fibrocartilage repair. The aim of this study is to compare the effects of 5 bone morphogenetic proteins (BMP...

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Bibliographic Details
Main Authors: Xueqin Gao, Nathaniel Wright, Matthieu Huard, Jian Tan, Joseph Ruzbarsky, Aiping Lu, Laura Chubb, Rocky Tuan, Marc J. Philippon, Yadong Wang, Johnny Huard
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-10-01
Series:Bioactive Materials
Subjects:
BMP2,4,6,7,9
In vitro chondrogenesis
Microfracture
Cartilage repair
Human bone marrow mesenchymal stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25002671
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