Platelet membrane biomimetic nanomedicine induces dual glutathione consumption for enhancing cancer radioimmunotherapy

Platelet membrane biomimetic nanomedicine induces dual glutathione consumption for enhancing cancer radioimmunotherapy

Radiotherapy (RT) is one of the most common treatments for cancer. However, intracellular glutathione (GSH) plays a key role in protecting cancer from radiation damage. Herein, we have developed a platelet membrane biomimetic nanomedicine (PMD) that induces double GSH consumption to enhance tumor ra...

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Bibliographic Details
Main Authors: Xiaopeng Li, Yang Zhong, Pengyuan Qi, Daoming Zhu, Chenglong Sun, Nan Wei, Yang Zhang, Zhanggui Wang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Dual GSH consumption
Cancer radioimmunotherapy
Platelet membrane biomimetic nanomedicine
Starvation therapy
Organic mesoporous silica nanoparticles
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177924000030
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