Investigation on the Binding and Conformational Change of All-trans-Retinoic Acid with Peptidyl Prolyl cis/trans Isomerase Pin1 Using Spectroscopic and Computational Techniques

Binding and conformational change of all-trans-retinoic acid (ATRA) with peptidyl prolyl cis/trans isomerase Pin1 were investigated systematically by spectroscopic and computational techniques under experimentally optimized physiological conditions. The intrinsic fluorescence of Pin1 was quenched th...

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Bibliographic Details
Main Authors: GuoFei Zhu, ShaoLi Lyu, Yang Liu, Chao Ma, Wang Wang
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Spectroscopy
Online Access:http://dx.doi.org/10.1155/2021/1012078
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