Large Multinodular Toxic Goiter: Is Surgery Always Necessary?
Patients suffering from multinodular toxic goiter (MNTG) are candidates to thyroidectomy or radioiodine 131I (131I) therapy. Thyroidectomy may be preferable especially when the volume of hyperfunctioning tissue is so large that a single administration of 131I is unlikely to cure the patient in terms...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2016/1320827 |
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| author | Roberto Negro Gabriele Greco |
| author_facet | Roberto Negro Gabriele Greco |
| author_sort | Roberto Negro |
| collection | DOAJ |
| description | Patients suffering from multinodular toxic goiter (MNTG) are candidates to thyroidectomy or radioiodine 131I (131I) therapy. Thyroidectomy may be preferable especially when the volume of hyperfunctioning tissue is so large that a single administration of 131I is unlikely to cure the patient in terms of nodule’s volume reduction and thyroid function. We describe the case of a 71-year-old man suffering from thyrotoxic state for the presence of two large hyperfunctioning thyroid nodules. As the patient refused surgery, at first we administered 600 MBq dose of 131I, which was unable to solve hyperthyroidism and local compressive symptoms. Then, before administering another 131I dose, the patient underwent a laser ablation treatment (LAT) in both nodules. After a significant shrinkage due to LAT, the patient received 400 MBq 131I. This procedure was able to definitely cure hyperthyroidism, to induce a significant reduction of nodules’ volume, and to render the patient asymptomatic for compressive symptoms. This case demonstrates that 131I preceded by LAT represents a valid alternative strategy to surgery, even in the presence of two large coexistent hot nodules. |
| format | Article |
| id | doaj-art-d1b321ef3a4a45339b0431d55505b0d2 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-d1b321ef3a4a45339b0431d55505b0d22025-02-03T07:25:46ZengWileyCase Reports in Endocrinology2090-65012090-651X2016-01-01201610.1155/2016/13208271320827Large Multinodular Toxic Goiter: Is Surgery Always Necessary?Roberto Negro0Gabriele Greco1Division of Endocrinology, “V. Fazzi” Hospital, Piazza F. Muratore, 73100 Lecce, ItalyDivision of Endocrinology, “V. Fazzi” Hospital, Piazza F. Muratore, 73100 Lecce, ItalyPatients suffering from multinodular toxic goiter (MNTG) are candidates to thyroidectomy or radioiodine 131I (131I) therapy. Thyroidectomy may be preferable especially when the volume of hyperfunctioning tissue is so large that a single administration of 131I is unlikely to cure the patient in terms of nodule’s volume reduction and thyroid function. We describe the case of a 71-year-old man suffering from thyrotoxic state for the presence of two large hyperfunctioning thyroid nodules. As the patient refused surgery, at first we administered 600 MBq dose of 131I, which was unable to solve hyperthyroidism and local compressive symptoms. Then, before administering another 131I dose, the patient underwent a laser ablation treatment (LAT) in both nodules. After a significant shrinkage due to LAT, the patient received 400 MBq 131I. This procedure was able to definitely cure hyperthyroidism, to induce a significant reduction of nodules’ volume, and to render the patient asymptomatic for compressive symptoms. This case demonstrates that 131I preceded by LAT represents a valid alternative strategy to surgery, even in the presence of two large coexistent hot nodules.http://dx.doi.org/10.1155/2016/1320827 |
| spellingShingle | Roberto Negro Gabriele Greco Large Multinodular Toxic Goiter: Is Surgery Always Necessary? Case Reports in Endocrinology |
| title | Large Multinodular Toxic Goiter: Is Surgery Always Necessary? |
| title_full | Large Multinodular Toxic Goiter: Is Surgery Always Necessary? |
| title_fullStr | Large Multinodular Toxic Goiter: Is Surgery Always Necessary? |
| title_full_unstemmed | Large Multinodular Toxic Goiter: Is Surgery Always Necessary? |
| title_short | Large Multinodular Toxic Goiter: Is Surgery Always Necessary? |
| title_sort | large multinodular toxic goiter is surgery always necessary |
| url | http://dx.doi.org/10.1155/2016/1320827 |
| work_keys_str_mv | AT robertonegro largemultinodulartoxicgoiterissurgeryalwaysnecessary AT gabrielegreco largemultinodulartoxicgoiterissurgeryalwaysnecessary |