Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures

Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures

Abstract Understanding human endometrial dynamics in the establishment of endometrial receptivity remains a challenge, which limits early diagnosis and treatment of endometrial-factor infertility. Here, we decode the endometrial dynamics of fertile women across the window of implantation and charact...

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Main Authors: Dandan Cao, Yijun Liu, Yanfei Cheng, Jue Wang, Bolun Zhang, Yanhui Zhai, Kongfu Zhu, Ye Liu, Ye Shang, Xiao Xiao, Yi Chang, Yin Lau Lee, William Shu Biu Yeung, Yuanhua Huang, Yuanqing Yao
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55419-z
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https://doi.org/10.1038/s41467-024-55419-z

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