Efficacy and safety of SGLT2 inhibitors in acute heart failure: a systematic review and meta-analysis of randomized controlled trials

Efficacy and safety of SGLT2 inhibitors in acute heart failure: a systematic review and meta-analysis of randomized controlled trials

BackgroundAcute heart failure (AHF) is a serious medical condition with considerable morbidity and mortality ranging from 20%–30% within the first month following hospital admission. We aimed to evaluate the efficacy and safety of sodium-glucose cotransporter-2 (SGLT2) inhibitors administered within...

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Main Authors: Ali Ibrahim Rahil, Tirth Bhavsar, Romman Fatima, Aparajitha Rajkumar, Joy Kumar, Hanif Al Majidan, Namrata Gajjala, Wodwentzky Lefranc, Fnu Deeksha, Harshitha Lingegowda, Muhammad Ehsan, Wajeeh Ur Rehman, Hasan Ahmad, Raheel Ahmed
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
SGLT2 inhibitors
acute heart failure
de-novo heart failure
systematic review
meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1543153/full
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https://www.frontiersin.org/articles/10.3389/fcvm.2025.1543153/full

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