Expression of Aldehyde Dehydrogenase 1A1 in Relapse-Associated Cells in Acute Myeloid Leukemia

Expression of Aldehyde Dehydrogenase 1A1 in Relapse-Associated Cells in Acute Myeloid Leukemia

In acute myeloid leukemia (AML) it is important to elucidate the biological events that lead from remission to relapse, which have a high probability of leading to an adverse disease outcome. The cancer stem cell marker aldehyde dehydrogenase 1 (ALDH1A1) is underexpressed in AML cells when compared...

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Bibliographic Details
Main Authors: Régis Costello, Garrett M. Dancik, Anaïs Dubiau, Lamia Madaci, Spiros Vlahopoulos
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
acute myeloid leukemia
leukemia stem cells
stem-like cells
relapse
reactive oxygen species
aldehyde dehydrogenase
Online Access:https://www.mdpi.com/2073-4409/14/13/1038
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