FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome

Purpose of Review. The aim of this review is to provide a case driven presentation of the presenting features and diagnostic criteria particularly focusing on the management of FPIES. It also summarises the natural history and resolution of cow’s milk induced FPIES. Data Sources. OvidSP Database was...

Full description

Saved in:
Bibliographic Details
Main Authors: Neha Khanna, Kirtika Patel
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2016/1621827
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832568247201824768
author Neha Khanna
Kirtika Patel
author_facet Neha Khanna
Kirtika Patel
author_sort Neha Khanna
collection DOAJ
description Purpose of Review. The aim of this review is to provide a case driven presentation of the presenting features and diagnostic criteria particularly focusing on the management of FPIES. It also summarises the natural history and resolution of cow’s milk induced FPIES. Data Sources. OvidSP Database was used to search for literature using the keywords food protein-induced enterocolitis and FPIES. Recent Findings. The diagnosis of FPIES is often delayed following two or more presentations. Symptoms in the acute form include profuse vomiting usually 2–6 hours following ingestion of food. Vomiting may or may not be accompanied by diarrhoea. Management involves removing the causal food protein from diet. There is some concomitance in cow’s milk and soya induced FPIES. Hence extensively hydrolysed formula is the milk of choice unless breast-feeding is carried out in which case that should be continued. Summary. FPIES is a complex form of non-IgE mediated food allergy. More awareness and knowledge of the condition are required to prevent misdiagnosis. Early diagnosis and removal of the culprit food protein improve the outcome. Good nutritional advice and clear management plans are important. More multicentre studies are required to reevaluate and produce consistent oral food challenge criteria and guidelines.
format Article
id doaj-art-d084088cf5da4fccaf7524da4f00d78a
institution Kabale University
issn 2090-6803
2090-6811
language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Case Reports in Pediatrics
spelling doaj-art-d084088cf5da4fccaf7524da4f00d78a2025-02-03T00:59:33ZengWileyCase Reports in Pediatrics2090-68032090-68112016-01-01201610.1155/2016/16218271621827FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis SyndromeNeha Khanna0Kirtika Patel1Lister Hospital, East and North Hertfordshire NHS Trust, Stevenage SG1 4AB, UKDepartment of Immunology, School of Medicine, Moi University, P.O. Box 4606, Eldoret 30100, KenyaPurpose of Review. The aim of this review is to provide a case driven presentation of the presenting features and diagnostic criteria particularly focusing on the management of FPIES. It also summarises the natural history and resolution of cow’s milk induced FPIES. Data Sources. OvidSP Database was used to search for literature using the keywords food protein-induced enterocolitis and FPIES. Recent Findings. The diagnosis of FPIES is often delayed following two or more presentations. Symptoms in the acute form include profuse vomiting usually 2–6 hours following ingestion of food. Vomiting may or may not be accompanied by diarrhoea. Management involves removing the causal food protein from diet. There is some concomitance in cow’s milk and soya induced FPIES. Hence extensively hydrolysed formula is the milk of choice unless breast-feeding is carried out in which case that should be continued. Summary. FPIES is a complex form of non-IgE mediated food allergy. More awareness and knowledge of the condition are required to prevent misdiagnosis. Early diagnosis and removal of the culprit food protein improve the outcome. Good nutritional advice and clear management plans are important. More multicentre studies are required to reevaluate and produce consistent oral food challenge criteria and guidelines.http://dx.doi.org/10.1155/2016/1621827
spellingShingle Neha Khanna
Kirtika Patel
FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome
Case Reports in Pediatrics
title FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome
title_full FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome
title_fullStr FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome
title_full_unstemmed FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome
title_short FPIES: Reviewing the Management of Food Protein-Induced Enterocolitis Syndrome
title_sort fpies reviewing the management of food protein induced enterocolitis syndrome
url http://dx.doi.org/10.1155/2016/1621827
work_keys_str_mv AT nehakhanna fpiesreviewingthemanagementoffoodproteininducedenterocolitissyndrome
AT kirtikapatel fpiesreviewingthemanagementoffoodproteininducedenterocolitissyndrome