Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera
Abstract Corneal ulcer is one of the most important ophthalmic emergencies. A portable, recordable, and smartphone-attachable slit-lamp device called the “Smart Eye Camera” (SEC) is introduced to compare evaluating corneal ulcers between the SEC and the conventional slit-lamp. A total of 110 partici...
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Nature Portfolio
2025-01-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-87820-z |
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| author | Sadegh Ghafarian Ahmad Masoumi Seyed Ali Tabatabaei Mehdi Yaseri Eisuke Shimizu Shintaro Nakayama Rohan Jeetendra Khemlani Hiroki Nishimura Hassan Asadigandomani |
| author_facet | Sadegh Ghafarian Ahmad Masoumi Seyed Ali Tabatabaei Mehdi Yaseri Eisuke Shimizu Shintaro Nakayama Rohan Jeetendra Khemlani Hiroki Nishimura Hassan Asadigandomani |
| author_sort | Sadegh Ghafarian |
| collection | DOAJ |
| description | Abstract Corneal ulcer is one of the most important ophthalmic emergencies. A portable, recordable, and smartphone-attachable slit-lamp device called the “Smart Eye Camera” (SEC) is introduced to compare evaluating corneal ulcers between the SEC and the conventional slit-lamp. A total of 110 participants were included in the study, consisting of 55 patients with corneal ulcers and 55 age- and gender-matched healthy volunteers as controls. The participants were first subjected to examination by a conventional slit lamp. The video recording with SEC and imaging with a slit lamp were done by a non-medical person. Both SEC videos and slit-lamp photos were reported by two independent ophthalmologists and compared with a slit-lamp examination as a gold standard. The average age of the study participants was 48.85 ± 20.45 years and 68 participants (61.8%) were male. All corneal ulcers were detected by two ophthalmologists using SEC. Ulcer size evaluated in slit lamp and SEC horizontally (Intraclass Correlation Coefficient (ICC); 0.90, 95% CI; 0.84–0.94) and vertically (ICC; 0.90, 95% CI; 0.84–0.94) is correlated about 90%. Hypopyon size (ICC; 0.95, 95% CI; 0.92–0.97), and corneal epithelial defect (CED) size horizontally (ICC; 0.94, 95% CI; 0.91–0.96) and vertically (ICC; 0.94, 95% CI; 0.91–0.96) also correlated about 94%. The infiltration pattern evaluated by SEC was consistent with the pattern evaluated in slit lamps in more than 80% of patients. The SEC is so accurate in diagnosing corneal ulcers and its reliability makes it a valuable telemedicine device. |
| format | Article |
| id | doaj-art-d07ee97c137a4545b70b7038dca137f8 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-d07ee97c137a4545b70b7038dca137f82025-01-26T12:26:17ZengNature PortfolioScientific Reports2045-23222025-01-0115111110.1038/s41598-025-87820-zClinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye CameraSadegh Ghafarian0Ahmad Masoumi1Seyed Ali Tabatabaei2Mehdi Yaseri3Eisuke Shimizu4Shintaro Nakayama5Rohan Jeetendra Khemlani6Hiroki Nishimura7Hassan Asadigandomani8Eye Research Center, Farabi Eye Hospital, Tehran University of Medical SciencesEye Research Center, Farabi Eye Hospital, Tehran University of Medical SciencesEye Research Center, Farabi Eye Hospital, Tehran University of Medical SciencesDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical SciencesDepartment of Ophthalmology, Keio University School of MedicineDepartment of Ophthalmology, Keio University School of MedicineOUI Inc.Department of Ophthalmology, Keio University School of MedicineEye Research Center, Farabi Eye Hospital, Tehran University of Medical SciencesAbstract Corneal ulcer is one of the most important ophthalmic emergencies. A portable, recordable, and smartphone-attachable slit-lamp device called the “Smart Eye Camera” (SEC) is introduced to compare evaluating corneal ulcers between the SEC and the conventional slit-lamp. A total of 110 participants were included in the study, consisting of 55 patients with corneal ulcers and 55 age- and gender-matched healthy volunteers as controls. The participants were first subjected to examination by a conventional slit lamp. The video recording with SEC and imaging with a slit lamp were done by a non-medical person. Both SEC videos and slit-lamp photos were reported by two independent ophthalmologists and compared with a slit-lamp examination as a gold standard. The average age of the study participants was 48.85 ± 20.45 years and 68 participants (61.8%) were male. All corneal ulcers were detected by two ophthalmologists using SEC. Ulcer size evaluated in slit lamp and SEC horizontally (Intraclass Correlation Coefficient (ICC); 0.90, 95% CI; 0.84–0.94) and vertically (ICC; 0.90, 95% CI; 0.84–0.94) is correlated about 90%. Hypopyon size (ICC; 0.95, 95% CI; 0.92–0.97), and corneal epithelial defect (CED) size horizontally (ICC; 0.94, 95% CI; 0.91–0.96) and vertically (ICC; 0.94, 95% CI; 0.91–0.96) also correlated about 94%. The infiltration pattern evaluated by SEC was consistent with the pattern evaluated in slit lamps in more than 80% of patients. The SEC is so accurate in diagnosing corneal ulcers and its reliability makes it a valuable telemedicine device.https://doi.org/10.1038/s41598-025-87820-zCorneal ulcerMicrobial keratitisSmart Eye CameraSECTelemedicine |
| spellingShingle | Sadegh Ghafarian Ahmad Masoumi Seyed Ali Tabatabaei Mehdi Yaseri Eisuke Shimizu Shintaro Nakayama Rohan Jeetendra Khemlani Hiroki Nishimura Hassan Asadigandomani Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera Scientific Reports Corneal ulcer Microbial keratitis Smart Eye Camera SEC Telemedicine |
| title | Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera |
| title_full | Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera |
| title_fullStr | Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera |
| title_full_unstemmed | Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera |
| title_short | Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera |
| title_sort | clinical evaluation of corneal ulcer with a portable and smartphone attachable slit lamp device smart eye camera |
| topic | Corneal ulcer Microbial keratitis Smart Eye Camera SEC Telemedicine |
| url | https://doi.org/10.1038/s41598-025-87820-z |
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