Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes

Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes

IntroductionAbnormalities of keratinocyte differentiation and impairment of permeability barrier are features of inflammatory skin diseases driven by Th1/Th17 and Th2 immune response, such as psoriasis and atopic dermatitis. We aimed at identifying the signature of the Th1/Th17 and Th2 environments...

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Main Authors: Alessia Cavallo, Emanuela Camera, Miriam Maiellaro, Grazia Bottillo, Sarah Mosca, Daniela Kovacs, Enrica Flori, Giorgia Cardinali
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Physiology
Subjects:
epidermal barrier
epidermal lipids
human keratinocytes cell line
3D human epidermal equivalent
Th1/Th17 cytokines
Th2 cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1387128/full
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https://www.frontiersin.org/articles/10.3389/fphys.2025.1387128/full

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