Synthesis of Oligonucleotide Conjugates and Phosphorylated Nucleotide Analogues: An Improvement to a Solid Phase Synthetic Approach

An improvement to our solid phase strategy to generate pharmacologically interesting molecule libraries is proposed here. The synthesis of new o-chlorophenol-functionalised solid supports with very high loading (0.18–0.22 meq/g for control pore glass (CPG) and 0.25–0.50 meq/g for TG) is reported. To...

Full description

Saved in:
Bibliographic Details
Main Authors: Valeria Romanucci, Armando Zarrelli, Lorenzo De Napoli, Cinzia Di Marino, Giovanni Di Fabio
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/469470
Tags: Add Tag
No Tags, Be the first to tag this record!