The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury
Perinatal brain injury frequently complicates preterm birth and leads to significant long-term morbidity. Cytokines and inflammatory cells are mediators in the common pathways associated with perinatal brain injury induced by a variety of insults, such as hypoxic-ischemic injury, reperfusion injury,...
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Format: | Article |
Language: | English |
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Wiley
2012-01-01
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Series: | Neurology Research International |
Online Access: | http://dx.doi.org/10.1155/2012/561494 |
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author | Ryan M. McAdams Sandra E. Juul |
author_facet | Ryan M. McAdams Sandra E. Juul |
author_sort | Ryan M. McAdams |
collection | DOAJ |
description | Perinatal brain injury frequently complicates preterm birth and leads to significant long-term morbidity. Cytokines and inflammatory cells are mediators in the common pathways associated with perinatal brain injury induced by a variety of insults, such as hypoxic-ischemic injury, reperfusion injury, toxin-mediated injury, and infection. This paper examines our current knowledge regarding cytokine-related perinatal brain injury and specifically discusses strategies for attenuating cytokine-mediated brain damage. |
format | Article |
id | doaj-art-d00fd008b4674b32bba7dcccc0a2b503 |
institution | Kabale University |
issn | 2090-1852 2090-1860 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Neurology Research International |
spelling | doaj-art-d00fd008b4674b32bba7dcccc0a2b5032025-02-03T05:43:56ZengWileyNeurology Research International2090-18522090-18602012-01-01201210.1155/2012/561494561494The Role of Cytokines and Inflammatory Cells in Perinatal Brain InjuryRyan M. McAdams0Sandra E. Juul1Division of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA 98195-6320, USADivision of Neonatology, Department of Pediatrics, University of Washington, Seattle, WA 98195-6320, USAPerinatal brain injury frequently complicates preterm birth and leads to significant long-term morbidity. Cytokines and inflammatory cells are mediators in the common pathways associated with perinatal brain injury induced by a variety of insults, such as hypoxic-ischemic injury, reperfusion injury, toxin-mediated injury, and infection. This paper examines our current knowledge regarding cytokine-related perinatal brain injury and specifically discusses strategies for attenuating cytokine-mediated brain damage.http://dx.doi.org/10.1155/2012/561494 |
spellingShingle | Ryan M. McAdams Sandra E. Juul The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury Neurology Research International |
title | The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury |
title_full | The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury |
title_fullStr | The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury |
title_full_unstemmed | The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury |
title_short | The Role of Cytokines and Inflammatory Cells in Perinatal Brain Injury |
title_sort | role of cytokines and inflammatory cells in perinatal brain injury |
url | http://dx.doi.org/10.1155/2012/561494 |
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