A quantitative spatial cell-cell colocalizations framework enabling comparisons between in vitro assembloids and pathological specimens
Abstract Spatial omics is enabling unprecedented tissue characterization, but the ability to adequately compare spatial features across samples under different conditions is lacking. We propose a quantitative framework that catalogs significant, normalized, colocalizations between pairs of cell subp...
Saved in:
Main Authors: | Gina Bouchard, Weiruo Zhang, Ilayda Ilerten, Irene Li, Asmita Bhattacharya, Yuanyuan Li, Winston Trope, Joseph B. Shrager, Calvin Kuo, Michael G. Ozawa, Amato J. Giaccia, Lu Tian, Sylvia K. Plevritis |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-02-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-55129-6 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A Rare Colocalization of Lichen Planus and Vitiligo
by: David Veitch, et al.
Published: (2015-01-01) -
Protocol for generating human assembloids to investigate thalamocortical and corticothalamic synaptic transmission and plasticity
by: Anjana Nityanandam, et al.
Published: (2025-03-01) -
Study of the Colocated Dual-Polarized MIMO Capacity Composed of Dipole and Loop Antennas
by: Dazhi Piao, et al.
Published: (2015-01-01) -
Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19Research in context
by: Hui Ying, et al.
Published: (2025-03-01) -
An Intercomparison of GPS RO Retrievals with Colocated Analysis and In Situ Observations within Tropical Cyclones
by: Henry R. Winterbottom, et al.
Published: (2010-01-01)