A note on the use of optimal control on a discrete time model of influenza dynamics

A discrete time Susceptible - Asymptomatic - Infectious - Treated - Recovered (SAITR) model is introduced in the context of influenza transmission.We evaluate the potential effect of control measures such as social distancing and antiviral treatment on the dynamics of a single outbreak.Optimal contr...

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Bibliographic Details
Main Authors: Paula A. González-Parra, Sunmi Lee, Leticia Velázquez, Carlos Castillo-Chavez
Format: Article
Language:English
Published: AIMS Press 2010-12-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.183
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Summary:A discrete time Susceptible - Asymptomatic - Infectious - Treated - Recovered (SAITR) model is introduced in the context of influenza transmission.We evaluate the potential effect of control measures such as social distancing and antiviral treatment on the dynamics of a single outbreak.Optimal control theory is applied to identify the best way of reducing morbidity and mortality at a minimal cost. The problem is solved by using a discrete version of Pontryagin's maximum principle. Numerical results show that dual strategies have stronger impact in the reduction of the final epidemic size.
ISSN:1551-0018