Exploration of drug repurposing for Mpox outbreaks targeting gene signatures and host-pathogen interactions

Exploration of drug repurposing for Mpox outbreaks targeting gene signatures and host-pathogen interactions

Abstract Monkeypox (Mpox) is a growing public health concern, with complex interactions within host systems contributing to its impact. This study employs multi-omics approaches to uncover therapeutic targets and potential drug repurposing opportunities to better understand Mpox’s molecular pathogen...

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Bibliographic Details
Main Authors: Saber Imani, Sargol Aminnezhad, Moslem Alikarami, Zahra Abedi, Iman Samei Mosleh, Mazaher Maghsoudloo, Zahra Taheri
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Monkeypox
Drug repurposing
Host-pathogen interaction
Weighted gene co-expression network analysis
Intracellular signaling pathways
Online Access:https://doi.org/10.1038/s41598-024-79897-9
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https://doi.org/10.1038/s41598-024-79897-9

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