Restoration of TP53 strategy via specific nanoparticles for ovarian cancer therapy

Abstract The p53 tumor suppressor gene, a master regulator of diverse cellular pathways, is frequently altered in various cancers. Loss of function in tumor suppressor genes is commonly associated with the onset/progression of cancer and treatment resistance. Currently, approaches for restoration of...

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Bibliographic Details
Main Authors: Menglei Zhang, Yuanyuan Gu, Fang Shen, Yingxin Gong, Zheng Gu, Keqin Hua, Guannan Zhou, Jingxin Ding
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-025-01672-9
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