Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus

Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus

Abstract Background The cytochrome P450s-mediated metabolic resistance and the target site insensitivity caused by the knockdown resistance (kdr) mutation in the voltage-gated sodium channel (vgsc) gene were the main mechanisms conferring resistance to deltamethrin in Culex quinquefasciatus from Tha...

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Main Authors: Saowanee Chamnanya, Benyapa Kiddela, Jassada Saingamsook, Woottichai Nachaiwieng, Nongkran Lumjuan, Pradya Somboon, Jintana Yanola
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Infectious Diseases of Poverty
Subjects:
Culex quinquefasciatus
Insecticide resistance
Pyrethroid
Deltamethrin
Cytochrome P450s
Knockdown resistance (kdr)
Online Access:https://doi.org/10.1186/s40249-024-01269-2
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https://doi.org/10.1186/s40249-024-01269-2

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