Performance of Xpert MTB/RIF ultra for the diagnosis of tuberculous meningitis in children using cerebrospinal fluid

Performance of Xpert MTB/RIF ultra for the diagnosis of tuberculous meningitis in children using cerebrospinal fluid

Abstract Rapid and reliable diagnostic tests for tuberculous meningitis (TBM) in children remain limited. This study evaluated the performance of Xpert MTB/RIF Ultra (Ultra), an improved version of Xpert MTB/RIF (Xpert), for detecting TBM in children using cerebrospinal fluid (CSF). Children (0–14 y...

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Main Authors: S. M. Mazidur Rahman, Rumana Nasrin, Senjuti Kabir, Faisal Kabir, Asif Md. Rezaur Rahman, Mohammad Khaja Mafij Uddin, A. S. M. Iftekhairul Islam, Razia Khatun, Shakil Ahmed, Md. Badrul Alam Mondal, Mohammad Sadekur Rahman Sarkar, Sayeeda Anwar, Javeed A. Shah, Sayera Banu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Tuberculous meningitis
Cerebrospinal fluid
Xpert MTB/RIF ultra
Xpert MTB/RIF
Diagnosis
Children
Online Access:https://doi.org/10.1038/s41598-025-97664-2
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https://doi.org/10.1038/s41598-025-97664-2

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