Safety and efficacy of HK-660S in patients with primary sclerosing cholangitis: A randomized double-blind phase 2a trial

Safety and efficacy of HK-660S in patients with primary sclerosing cholangitis: A randomized double-blind phase 2a trial

Background/Aims A clinical unmet need persists for medications capable of modulating the progression of primary sclerosing cholangitis (PSC). This study aimed to assess the clinical feasibility of HK-660S (beta-lapachone) in PSC. Methods In this multicenter, randomized, double-blind, placebo-control...

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Main Authors: Woo Hyun Paik, Joo Kyung Park, Moon Jae Chung, Gunn Huh, Ce Hwan Park, Sang Hyub Lee, Heon Se Jeong, Hee Jin Kim, Do Hyun Park
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2025-01-01
Series:Clinical and Molecular Hepatology
Subjects:
primary sclerosing cholangitis
lapachone
cholangiopancreatography, magnetic resonance
alkaline phosphatase
nicotinamide adenine dinucleotide
Online Access:http://e-cmh.org/upload/pdf/cmh-2024-0629.pdf
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http://e-cmh.org/upload/pdf/cmh-2024-0629.pdf

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