Drug molecular representations for drug response predictions: a comprehensive investigation via machine learning methods

Abstract The integration of drug molecular representations into predictive models for Drug Response Prediction (DRP) is a standard procedure in pharmaceutical research and development. However, the comparative effectiveness of combining these representations with genetic profiles for DRP remains unc...

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Bibliographic Details
Main Authors: Meisheng Xiao, Qianhui Zheng, Paul Popa, Xinlei Mi, Jianhua Hu, Fei Zou, Baiming Zou
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-84711-7
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