Creating burdock polysaccharide-oleanolic acid-ursolic acid nanoparticles to deliver enhanced anti-inflammatory effects: fabrication, structural characterization and property evaluation

Creating burdock polysaccharide-oleanolic acid-ursolic acid nanoparticles to deliver enhanced anti-inflammatory effects: fabrication, structural characterization and property evaluation

This study explored the potential of polysaccharides from Actium lappa (ALPs) as natural wall materials for producing ALP-based nanoparticles to deliver poorly water-soluble oleanolic acid (OA) and ursolic acid (UA). Encapsulating OA+UA with ALPs (ALP:OA+UA, 50:1; OA:UA, 1:1) changed the crystalline...

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Bibliographic Details
Main Authors: Shanshan Zhu, Zhichang Qiu, Xuguang Qiao, Geoffrey I.N. Waterhouse, Wenqing Zhu, Wenting Zhao, Qiuxia He, Zhenjia Zheng
Format: Article
Language:English
Published: Tsinghua University Press 2023-03-01
Series:Food Science and Human Wellness
Subjects:
Encapsulation
Structural features
Particle size
Zeta potential
Thermodynamic properties
In vivo verification
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453022001598
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http://www.sciencedirect.com/science/article/pii/S2213453022001598

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