Correlation Analysis of Ocular Symptoms and Signs in Patients with Dry Eye
Purpose. To analyze the correlations between the ocular surface signs and symptoms in patients with dry eye. Methods. In this observational study, 176 dry eye patients, including 60 males and 116 females, were enrolled and their dry eye symptoms and ocular signs were observed. Partial correlation an...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/1247138 |
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| author | Hang Song Mingzhou Zhang Xiaodan Hu Kaixiu Li Xiaodan Jiang Yan Liu Huibin Lv Xuemin Li |
| author_facet | Hang Song Mingzhou Zhang Xiaodan Hu Kaixiu Li Xiaodan Jiang Yan Liu Huibin Lv Xuemin Li |
| author_sort | Hang Song |
| collection | DOAJ |
| description | Purpose. To analyze the correlations between the ocular surface signs and symptoms in patients with dry eye. Methods. In this observational study, 176 dry eye patients, including 60 males and 116 females, were enrolled and their dry eye symptoms and ocular signs were observed. Partial correlation analysis was conducted between OSDI score and each ocular surface sign, and the correlations were further discussed in different age groups. Then multiple linear regression analysis was used to further explore the influence of these signs on OSDI score. Results. Our correlation analyses showed that rounding of lid margins, notching of lid margins, vascularity of lid margins, hyperkeratinization, plugging of orifices, main duct dropout, and conjunctival congestion all had a positive correlation with OSDI score, while main duct number (central 1 cm) and BUT had a negative one. Further analysis suggested that these correlations varied in different age groups. Multiple linear regression analysis indicated that main duct number (central 1 cm), rounding of lid margins, and hyperkeratinization significantly affected OSDI score. Conclusions. Close attention should be paid to the morphology and structure of the eyelid margin and the function of meibomian gland in the diagnosis, treatment, and follow-up of dry eye diseases. |
| format | Article |
| id | doaj-art-cf6eba3a3a3a4fc990f4b7ae39f5185d |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-cf6eba3a3a3a4fc990f4b7ae39f5185d2025-02-03T01:22:59ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/12471381247138Correlation Analysis of Ocular Symptoms and Signs in Patients with Dry EyeHang Song0Mingzhou Zhang1Xiaodan Hu2Kaixiu Li3Xiaodan Jiang4Yan Liu5Huibin Lv6Xuemin Li7Department of Ophthalmology, Peking University Third Hospital, Beijing, ChinaDepartment of Ophthalmology, Peking University Third Hospital, Beijing, ChinaDepartment of Ophthalmology, Peking University Third Hospital, Beijing, ChinaDepartment of Ophthalmology, Peking University Third Hospital, Beijing, ChinaDepartment of Ophthalmology, Peking University Third Hospital, Beijing, ChinaDepartment of Ophthalmology, Peking University Third Hospital, Beijing, ChinaDepartment of Ophthalmology, Peking University Third Hospital, Beijing, ChinaDepartment of Ophthalmology, Peking University Third Hospital, Beijing, ChinaPurpose. To analyze the correlations between the ocular surface signs and symptoms in patients with dry eye. Methods. In this observational study, 176 dry eye patients, including 60 males and 116 females, were enrolled and their dry eye symptoms and ocular signs were observed. Partial correlation analysis was conducted between OSDI score and each ocular surface sign, and the correlations were further discussed in different age groups. Then multiple linear regression analysis was used to further explore the influence of these signs on OSDI score. Results. Our correlation analyses showed that rounding of lid margins, notching of lid margins, vascularity of lid margins, hyperkeratinization, plugging of orifices, main duct dropout, and conjunctival congestion all had a positive correlation with OSDI score, while main duct number (central 1 cm) and BUT had a negative one. Further analysis suggested that these correlations varied in different age groups. Multiple linear regression analysis indicated that main duct number (central 1 cm), rounding of lid margins, and hyperkeratinization significantly affected OSDI score. Conclusions. Close attention should be paid to the morphology and structure of the eyelid margin and the function of meibomian gland in the diagnosis, treatment, and follow-up of dry eye diseases.http://dx.doi.org/10.1155/2017/1247138 |
| spellingShingle | Hang Song Mingzhou Zhang Xiaodan Hu Kaixiu Li Xiaodan Jiang Yan Liu Huibin Lv Xuemin Li Correlation Analysis of Ocular Symptoms and Signs in Patients with Dry Eye Journal of Ophthalmology |
| title | Correlation Analysis of Ocular Symptoms and Signs in Patients with Dry Eye |
| title_full | Correlation Analysis of Ocular Symptoms and Signs in Patients with Dry Eye |
| title_fullStr | Correlation Analysis of Ocular Symptoms and Signs in Patients with Dry Eye |
| title_full_unstemmed | Correlation Analysis of Ocular Symptoms and Signs in Patients with Dry Eye |
| title_short | Correlation Analysis of Ocular Symptoms and Signs in Patients with Dry Eye |
| title_sort | correlation analysis of ocular symptoms and signs in patients with dry eye |
| url | http://dx.doi.org/10.1155/2017/1247138 |
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