Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer Tissues
Breast cancer is the major cause of cancer morbidity and mortality between women in the world. Metals involved in environmental toxicology are closely related to tumor growth and cancer. On the other hand, some metals such as selenium have anticarcinogenic properties. The aim of this study is to det...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Toxicology |
| Online Access: | http://dx.doi.org/10.1155/2014/413870 |
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| author | Mehrnoosh Mohammadi Alireza Riyahi Bakhtiari Saber Khodabandeh |
| author_facet | Mehrnoosh Mohammadi Alireza Riyahi Bakhtiari Saber Khodabandeh |
| author_sort | Mehrnoosh Mohammadi |
| collection | DOAJ |
| description | Breast cancer is the major cause of cancer morbidity and mortality between women in the world. Metals involved in environmental toxicology are closely related to tumor growth and cancer. On the other hand, some metals such as selenium have anticarcinogenic properties. The aim of this study is to determine the concentration of cadmium, lead, mercury, and selenium in separated parts of tegmen, tumor, tumor adiposity, and tegmen adiposity of 14 breast cancer tissues which have been analyzed by graphite furnace atomic absorption (AA-670) and ICP-OES (ULTIMA 2CE). Our results show that Se and Hg have maximum and minimum concentration, respectively. Statistical analysis reveals no significant differences between metal accumulations in different parts of cancer tissues (P>0.05) and this observation might be due to the close relation of separated parts of fatty breast organ. Thus, we could conclude that a high level of these heavy metals is accumulated in Iranian cancerous breasts and their presence can be one of the reasons of cancer appearance. |
| format | Article |
| id | doaj-art-cf67a52dd0344de0a7a1e13a5ee5075d |
| institution | Kabale University |
| issn | 1687-8191 1687-8205 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Toxicology |
| spelling | doaj-art-cf67a52dd0344de0a7a1e13a5ee5075d2025-02-03T01:22:59ZengWileyJournal of Toxicology1687-81911687-82052014-01-01201410.1155/2014/413870413870Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer TissuesMehrnoosh Mohammadi0Alireza Riyahi Bakhtiari1Saber Khodabandeh2Environmental Forensic Laboratory, Department of Environmental Sciences, Faculty of Natural Resource and Marine Science, Tarbiat Modares University, P.O. Box 64414-356, Noor, Mazandaran, IranEnvironmental Forensic Laboratory, Department of Environmental Sciences, Faculty of Natural Resource and Marine Science, Tarbiat Modares University, P.O. Box 64414-356, Noor, Mazandaran, IranFaculty of Marine Science, Tarbiat Modares University, Tehran, IranBreast cancer is the major cause of cancer morbidity and mortality between women in the world. Metals involved in environmental toxicology are closely related to tumor growth and cancer. On the other hand, some metals such as selenium have anticarcinogenic properties. The aim of this study is to determine the concentration of cadmium, lead, mercury, and selenium in separated parts of tegmen, tumor, tumor adiposity, and tegmen adiposity of 14 breast cancer tissues which have been analyzed by graphite furnace atomic absorption (AA-670) and ICP-OES (ULTIMA 2CE). Our results show that Se and Hg have maximum and minimum concentration, respectively. Statistical analysis reveals no significant differences between metal accumulations in different parts of cancer tissues (P>0.05) and this observation might be due to the close relation of separated parts of fatty breast organ. Thus, we could conclude that a high level of these heavy metals is accumulated in Iranian cancerous breasts and their presence can be one of the reasons of cancer appearance.http://dx.doi.org/10.1155/2014/413870 |
| spellingShingle | Mehrnoosh Mohammadi Alireza Riyahi Bakhtiari Saber Khodabandeh Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer Tissues Journal of Toxicology |
| title | Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer Tissues |
| title_full | Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer Tissues |
| title_fullStr | Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer Tissues |
| title_full_unstemmed | Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer Tissues |
| title_short | Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer Tissues |
| title_sort | concentration of cd pb hg and se in different parts of human breast cancer tissues |
| url | http://dx.doi.org/10.1155/2014/413870 |
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