Implanted Microneedles Loaded with Sparfloxacin and Zinc‐Manganese Sulfide Nanoparticles Activates Immunity for Postoperative Triple‐Negative Breast Cancer to Prevent Recurrence and Metastasis

Implanted Microneedles Loaded with Sparfloxacin and Zinc‐Manganese Sulfide Nanoparticles Activates Immunity for Postoperative Triple‐Negative Breast Cancer to Prevent Recurrence and Metastasis

Abstract Recent investigations have underscored the significant role of manganese ions (Mn2+) in immunization, particularly through the activation of the cGAS‐STING pathway, which enhances antitumor immune responses. However, the rapid metabolism of free Mn2+ following administration limits its effe...

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Bibliographic Details
Main Authors: Zhaoyou Chu, Wang Zheng, Wanyue Fu, Jun Liang, Wanni Wang, Lingling Xu, Xiaohua Jiang, Zhengbao Zha, Haisheng Qian
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
lung metastasis
microneedle
nanomedicine
triple negative breast cancer
Online Access:https://doi.org/10.1002/advs.202416270
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