The relationship between mutation carriage of BRCA1/2 and clinicopathological characteristics in women with breast cancer – experience from a diagnostic centre in Turkey

The relationship between mutation carriage of BRCA1/2 and clinicopathological characteristics in women with breast cancer – experience from a diagnostic centre in Turkey

The 5–10% of breast cancers (BC) are hereditary, and BRCA1/2 are causative in 25% of those inherited. It was aimed to examine the BRCA1/2 genotype-BC phenotype relationship. In 170 female patients with BC, BRCA1/2 genes were investigated using Next Generation Sequencing. Demographic and clinicopath...

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Bibliographic Details
Main Authors: Neslihan Duzkale, Onur Can Guler, Suat Kutun, Canan Emiroglu, Serdar Saridemir, Aysun Gokce, Olcay Kandemir, Tugba Taskın Turkmenoglu, Serap Yorubulut, Bahadır Kulah
Format: Article
Language:English
Published: Termedia Publishing House 2024-09-01
Series:Polish Journal of Pathology
Subjects:
breast cancer
triple-negative
progesterone receptor
oestrogen receptor
brca1
brca2.
Online Access:https://www.termedia.pl/The-relationship-between-mutation-carriage-of-BRCA1-2-and-clinicopathological-characteristics-in-women-with-breast-cancer-experience-from-a-diagnostic-centre-in-Turkey,55,54732,1,1.html
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https://www.termedia.pl/The-relationship-between-mutation-carriage-of-BRCA1-2-and-clinicopathological-characteristics-in-women-with-breast-cancer-experience-from-a-diagnostic-centre-in-Turkey,55,54732,1,1.html

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