Impact of the NK Cell Receptor LIR-1 (ILT-2/CD85j/LILRB1) on Cytotoxicity against Multiple Myeloma

Impact of the NK Cell Receptor LIR-1 (ILT-2/CD85j/LILRB1) on Cytotoxicity against Multiple Myeloma

The role of different receptors in natural-killer- (NK-) cell-mediated cytotoxicity against multiple myeloma (MM) cells is unknown. We investigated if an enhancement of NK-cell-mediated cytotoxicity against MM could be reached by blocking of the inhibitory leukocyte immunoglobulin-like receptor 1 (L...

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Bibliographic Details
Main Authors:	Silke Heidenreich, Christine zu Eulenburg, York Hildebrandt, Thomas Stübig, Heidi Sierich, Anita Badbaran, Thomas H. Eiermann, Thomas M. C. Binder, Nicolaus Kröger
Format:	Article
Language:	English
Published:	Wiley 2012-01-01
Series:	Clinical and Developmental Immunology
Online Access:	http://dx.doi.org/10.1155/2012/652130
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