TLR4 Asp299Gly SNP (rs4986790) Protects from Periodontal Inflammatory Destruction by Altering TLR4 Susceptibility to LPS Stimulation

Periodontitis is a multifactorial disease linked to host immune response and genetic predisposition. The TLR4 Asp299Gly single-nucleotide polymorphism (SNP, rs4986790) has been associated with altered responses to bacterial lipopolysaccharide (LPS) and may influence susceptibility to inflammatory di...

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Bibliographic Details
Main Authors: Franco Cavalla, Claudia C. Biguetti, Ariadne Letra, Renato M. Silva, Alexandre R. Vieira, Franz J. Strauss, Gustavo P. Garlet
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biology
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Online Access:https://www.mdpi.com/2079-7737/14/7/894
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