Elevated levels of exogenous prolactin promote inflammation at the maternal-fetal interface via the JAK2/STAT5B signaling axis

The placenta is a unique organ with various immunological and endocrinological roles that modulate maternal and fetal physiology to promote maternal-fetal tolerance, pregnancy maintenance, and parturition at term. During pregnancy, the hormone prolactin (PRL) is constitutively secreted by the placen...

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Bibliographic Details
Main Authors: Alycia Williams, Daniel J. Hossack, Nia Thompson, Yul Eum Sim, Cristina Wilson, Viviane Schuch, Tiffany Hailstorks, Rana Chakraborty, Erica L. Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1496610/full
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