The Role of Ca2+/PI3K/Akt/eNOS/NO Pathway in Astragaloside IV–Induced Inhibition of Endothelial Inflammation Triggered by Angiotensin II

Inflammation induced by angiotensin II (Ang II) is a key event in the progression of numerous cardiovascular diseases. Astragaloside IV (AS-IV), a glycoside extracted from Astragalus membranaceus Bunge, has been shown to inhibit Ang II–induced inflammatory responses in vivo. However, the mechanisms...

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Bibliographic Details
Main Authors: Shiyu Zhang, Shijie Li, Shiyang Xie, Lin Cui, Yuan Gao, Youping Wang
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2024/3193950
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