Retrospective analysis of 300 microbial cell-free DNA sequencing results in routine blood stream infection diagnostics

Retrospective analysis of 300 microbial cell-free DNA sequencing results in routine blood stream infection diagnostics

IntroductionBloodstream infections are a critical challenge worldwide due to the slow turnaround time of conventional microbiological tests for detecting bacteremia in septic patients. Noscendo GmbH (Duisburg, Germany) has developed the CE/IVD pipeline DISQVER for clinical metagenomics testing based...

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Bibliographic Details
Main Authors: Claudio Neidhöfer, Niklas Klein, Aylin Yürüktümen, Tessa Hattenhauer, Rebekka Mispelbaum, Christian Bode, Tobias A. W. Holderried, Achim Hoerauf, Marijo Parčina
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
sepsis
bacteremia
blood culture
molecular diagnostic techniques
next generation sequencing
clinical metagenomics
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1504262/full
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