Human placenta mesenchymal stromal cells alleviate intestinal inflammation and repair intestinal barrier function by activating AMPK-FXR pathway

Abstract Crohn’s disease (CD) has a complex pathogenesis; there is currently no effective treatment. Mesenchymal stromal cells (MSCs) are a potential therapeutic option for CD. It is important to systematically evaluate the safety and effectiveness of MSCs and their mechanism for the treatment of CD...

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Bibliographic Details
Main Authors: Ruo Wang, Bing Feng, Qigu Yao, Qiaoling Pan, Jiong Yu, Chaoxu Liu, Jinhai Wang, Lanjuan Li, Hongcui Cao, Jue Xie
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08261-y
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